Microbial expression systems for membrane proteins
نویسندگان
چکیده
منابع مشابه
different expression systems for production of hcv structural proteins
hepatitis c virus (hcv) is an important agent causing chronic liver infection, which often leads to liver cirrhosis and lethal hepatocellular carcinoma (hcc). at present, there is no effective hcv vaccine for prevention of hepatic disease and the standard treatment is neither economical nor fully effective in all the patients. however, vaccination based on structural and nonstructural proteins ...
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تخمین دقیق مشخصات کانال در سیستم های مخابراتی یک امر مهم محسوب می گردد. این امر به ویژه در کانال های بیسیم با خاصیت فرکانس گزینی و زمان گزینی شدید، چالش بزرگی است. مقالات متعدد پر از روش های مبتکرانه ای برای طراحی و آنالیز الگوریتم های تخمین کانال است که بیشتر آنها از روش های خاصی استفاده می کنند که یا دارای عملکرد خوب با پیچیدگی محاسباتی بالا هستند و یا با عملکرد نه چندان خوب پیچیدگی پایینی...
Heterologous Expression and Purification Systems for Structural Proteomics of Mammalian Membrane Proteins
Membrane proteins (MPs) are responsible for the interface between the exterior and the interior of the cell. These proteins are implicated in numerous diseases, such as cancer, cystic fibrosis, epilepsy, hyperinsulinism, heart failure, hypertension and Alzheimer's disease. However, studies on these disorders are hampered by a lack of structural information about the proteins involved. Structura...
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With the advent of our ability to clone and express a foreign gene in the heterologous host, came a remarkable capability to make almost any protein in abundant quantity to be used as therapeutic or diagnostic agents. It quickly led to the realization that proteins made in different hosts are different in many ways, particularly in their post-translation modifications. In this review a variety ...
متن کاملExpression and purification of membrane proteins.
Approximately 30% of a genome encodes for membrane proteins. They are one of the most important classes of proteins in that they can receive, differentiate, and transmit intra- and intercellular signals. Some examples of classes of membrane proteins include cell-adhesion molecules, translocases, and receptors in signaling pathways. Defects in membrane proteins may be involved in a number of ser...
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ژورنال
عنوان ژورنال: Methods
سال: 2018
ISSN: 1046-2023
DOI: 10.1016/j.ymeth.2018.04.009